Hand cream is applied to the hands to moisturise and protect them. Hand cream can also be applied to other body parts like the elbows, knees, and feet. Hand cream will typically contain a moisturiser, such as glycerine or shea butter. Other ingredients may include oils, fragrance, vitamins A and D, aloe vera extract, or camphor.

Hand creams are available in various textures for different needs. Some are thicker for more extreme dryness while others are lighter for everyday use. The thickness of hand cream can also depend on the climate where it is being used as well as the time of year.