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Sudafed is a widely recognised over-the-counter medication used to relieve nasal congestion caused by colds, allergies, and sinus infections. The active ingredient in Sudafed is pseudoephedrine, a decongestant that works by shrinking the blood vessels in the nasal passages, thereby reducing swelling and congestion. It is important to use Sudafed as directed and consult with a healthcare provider if you have any underlying health conditions or are taking other medications.