Pharmaceris V is a pioneering approach to the problem of depigmentation based on a unique combination of active substances - rosmarinic acid and thioproline, showing a global effect on skin cells. The complex protects against free radicals, has an anti-inflammatory effect on IL-6 and protects cell structures against oxidative damage. Preparations enhanced by the action of naringenin stimulating mitochondria and involved in silencing the genes of vitiligo, in combination with VDR activator stimulating the vitamin D receptor promote skin re-pigmentation. As a result, the preparations even out the skin tone and prevent the expansion and formation of new whitening lesions.