Do not shake. After cleansing skin, apply white sulfur sediment with cotton swab directly onto blemish at bedtime as an overnight treatment. Limit to one application daily to avoid drying out skin.caution. For external, adult use only. avoid contact with eyes. If skin irritation occurs, discontinue use and consult a doctor. Using acne medication in conjunction with this product may increase drying and irritation to the skin. Only one topical acne medication should be used at a time unless directed by a doctor.